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Susan Whitfield-Gabrieli, Ph.D.

  • Research Scientist, Martinos Imaging Center, McGovern Institute for Brain Research
  • Research Scientist, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
Dr. Susan Whitfield-Gabrieli - Send email to swg@mit.edu

Susan Whitfield-Gabrieli is a Research Scientist in the Martinos Imaging Center at the McGovern Institute for Brain Research and in the Department of Brain and Cognitive Sciences at MIT. She also serves as teaching faculty at MIT and Harvard Medical School.   She investigates how analyses of brain imaging data can shed light on the neural mechanisms subserving normal cognition and how disturbances of those mechanisms impair cognition in neurological and psychiatric diseases. Her research interests include: 1) psychiatric disorders such as schizophrenia and depression; 2) age-related disorders such as Alzheimer’s disease and mild cognitive impairment (MCI); and 3) developmental disorders such as dyslexia. Her research focuses on the development of quantitative methods to analyze data from functional magnetic resonance imaging (fMRI), resting-state functional fMRI (rs-fcMRI) as well as combinging  multimodal imaging techniques (fMRI, rs-fcMRI, DTI, EEG/ERP) to investigate functional and anatomical connectivity as well as exploring novel approaches to multimodal integration.

Representative Publications:

Whitfield-Gabrieli, S. (2012) “Assessment of Default Mode Network Activity and Connectivity in Psychopathology” Annual Review of Clinical Psychology.

Whitfield-Gabrieli S, Moran J.M, Triantafyllou.C., Saxe, R., Gabrieli .J.D.E. (2010).  Associations and dissociations between default and self- reference networks in the human Brain. NeuroImage.

Chai XJ, Castañón AN, Ongür D, Whitfield-Gabrieli S. (2012) Anticorrelations in resting state networks without global signal regression. Neuroimage 59: 1420-8.

Whitfield-Gabrieli, S.,  Thermenos, H., Milanovic, S., Tsuang, M., Faraone, S., McCarley, R., Shenton, M., Green, A., LaViolette, P., Wojcik, J., Gabrieli, J.D.E., Seidman, L. (2009).  Hyperactivity and Hyperconnectivity of the Default Network in Schizophrenia and in First Degree Relatives of Persons with Schizophrenia, Proc Natl Acad Sci USA  106, 1279-84.

Chai, J., Whitfield-Gabrieli, S., Castañón, A.., Gabrieli,.D.J., McCarthy, J.M., Cohen, B.M.,  Shinn A.K.,  Öngür, D. (2011).  Abnormal ventral and dorsal lateral prefrontal resting-state connectivity patterns in bipolar disorder and schizophrenia. Neuropsychopharmacology.

Goldstein JM, Jerram M, Abbs B, Whitfield-Gabrieli S, Makris N.  (2010)  Sex differences in stress response circuitry activation dependent on female hormonal cycle. J Neurosci. 2010 Jan 13;30(2):431-8.

Holsen LM, Spaeth SB, Lee JH, Ogden LA, Klibanski A, Whitfield-Gabrieli S, Goldstein JM. (2011) Stress response circuitry hypoactivation related to hormonal dysfunction in women with major depression. J Affect Disord.131(1-3):379-87.

Hoeft, F., McCandliss, B., Black, J., Gamtman, A., Zakerani, N., Hulme, C., Lyytinen, H., Whitfield-Gabrieli, S., Glover, G., Reiss, A.L., Gabrieli, J.D.E. (2011) Neural systems predicting long-term outcome in dyslexia. Proceedings of the National Academy of Sciences of the United States of America, 108, 361-366.

Biswal, B,  Mennes, M., Zuo, X., Gohel, S., Kelly, C., Smith,S.,  Beckmann, C.,  Adelstein, J.,  Buckner, R.,  Colcombe, S.,  Dogonowski, A.,  Ernst, M.,  Fair, D.,  Hampson, M.,  Hoptman, M.,  Hyde, J.,  Kiviniemi, V.,  Kötter, R.,  Li, S.,  Lin, C., Lowe, M.,  Mackay, C.,  Madden, D.,  Madsen, K.,  Margulies, D.,  Mayberg, H. S.,  McMahon, K.,  Monk, C..,  Mostofsky, S., Nagel, B.,  Pekar, J.,  Peltier, S.,  Petersen, S. E.,  Riedl,V.,  Rombouts, S.,  Rypma, B.,  Schlaggar, B. L.,  Seidler, S., Siegle, G.,  Sorg, C., Teng, G.,  Veijola, J.,  Villringer, A., Walter, M.,  Wang, L.,  Weng, X.,  Whitfield-Gabrieli, S., Williamson,P.,  Windischberger, C.,  Zang, Y.,  Zhang, H.,  Castellanos, F. X., Milham, M. P., (2010) Towards discovery science of human brain function. Proc Natl Acad Sci USA.

Ford, J.M., Gray, E.M., Whitfield, S.L., Turken, A.U., Glover, G., Faustman, W.O., and Mathalon, D.H. (2004). Combining ERP and fMRI data to understand response inhibition in schizophrenia. Archives of General Psychiatry, 61, 119-129.

Publications by Dr. Whitfield-Gabrieli