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Jordan Smoller, M.D., Sc.D.

  • Director, Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital
  • Associate Professor of Psychiatry, Harvard Medical School
Dr. Jordan Smoller - Send email to jordan_smoller@hms.harvard.edu

Dr. Jordan Smoller is Associate Vice Chair of the MGH Department of Psychiatry and Director of Psychiatric Genetics. He is Associate Professor of Psychiatry at Harvard Medical School and Associate Professor in the Department of Epidemiology at the Harvard School of Public Health in Boston.  He is Director of the Psychiatric and Neurodevelopmental Genetics Unit at the MGH Center for Human Genetics Research and a founding faculty member of the MGH Mood and Anxiety Disorders Institute. Dr. Smoller also serves as co-director of the Genetics and Genomics Unit of the MGH Clinical Research Program. At Harvard Medical School, he is Director of the Translational Genetics and Bioinformatics Program of the Harvard Catalyst.  He is also a Senior Scientist at the Stanley Center for Psychiatric Research of the Broad Institute of Harvard and MIT.
He earned his undergraduate degree from Harvard College, and MD from Harvard Medical School. After completing his clinical training in psychiatry at McLean Hospital, he earned a doctoral degree in psychiatric and genetic epidemiology from the Harvard School of Public Health and trained as a postdoctoral fellow in the NIMH Training Program in Psychiatric Genetics.

He is an author of more than 120 scientific articles, book chapters and reviews; the recipient of numerous research awards; and a principal investigator on NIH-funded studies of the genetics of anxiety and the genetics of bipolar disorder, major depression and schizophrenia. Dr. Smoller is an Associate Editor of the American Journal of Medical Genetics-B (Neuropsychiatric Genetics) and editor of the volume, Psychiatric Genetics: Applications in Clinical Practice. The focus of Dr. Smoller’s research interests has been the identification of genetic determinants of childhood and adult psychiatric disorders as well as neural phenotypes underlying risk for these disorders. Major research projects include studies examining the phenotypic spectrum of susceptibility genes and the impact of genetic variation on brain structure and function.  Dr. Smoller and colleagues have also been studying pharmacogenetic predictors of treatment response and the ways in which advances in genetics may impact clinical practice in psychiatry.

Publications by Dr. Smoller